Transport Phenomena in Biological Systems

Description

The efficient transport of molecules is essential for the normal function of cells and organs and the design of devices for medical applications and biotechnology. Transport Phenomena in Biological Systems provides an introduction to the integrated study of transport processes and their biological applications.

The book consists of four sections, which cover physiological fluid mechanics, mass transport, biochemical interactions and reactions and the effect of mass transfer, and transport in organs and whole organisms. In order to provide students with a firm understanding of biological transport processes, engineering concepts are provided within the context of specific biological problems. Examples and problems elaborate on the concepts in the text or develop new concepts. The introductory chapter presents a brief overview of transport processes at the cell and tissue level and relevant concepts in cell biology and physiology are presented throughout the text. An appendix provides an overview of relevant mathematical concepts used in the text. The problems at the end of each chapter require either analytical solution or numerical solution using MATLAB^®.

This book can be used for both introductory and advanced courses. Advanced topics covered include transport in the kidney, oxygen transport, receptor-mediated processes, cell adhesion, transport of drugs in tumors, and whole body pharmacokinetic models. References are provided for further study.

• Numerous worked example and homework problems in each chapter–Include analytical and numerical solutions.

  • Elaborates upon problems discussed in the text, and addresses new biomedical problems.

• Focus on the interrelationship among biological, chemical, and physical processes.

  • Presents these relationships in the context of biomedical applications to provide students with the insights needed to address unsolved and important transport problems.

• Emphasis on analytical solutions.

  • Provides physical insights important for introductory material and a first-order level of understanding.

• Discussions of concept application–Immediately follows the development of each engineering concept.

  • Gives students an understanding of the specific topics presented as well as the application of the concept to important biological problems.

• References to current literature.

  • Offers students more detailed analysis.

• Part-opening chapter.

  • Develops the relevant engineering concepts in terms of a specific biological context.

• Book-concluding chapter.

  • Synthesizes concepts from all three parts by considering several examples of whole-body transport.

The authors are faculty members in the Department of Biomedical Engineering at Duke University.  The authors are leaders in their respective fields of research and their research has involved various aspects of momentum and mass transport related to biological phenomena and technologies.

 

For one-semester, advanced undergraduate/graduate courses in Biotransport Engineering.

Presenting engineering fundamentals and biological applications in a unified way, this text provides students with the skills necessary to develop and critically analyze models of biological transport and reaction processes. It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems.

 

For one-semester, advanced undergraduate/graduate courses in Biotransport Engineering.

Presenting engineering fundamentals and biological applications in a unified way, this text provides students with the skills necessary to develop and critically analyze models of biological transport and reaction processes. It covers topics in fluid mechanics, mass transport, and biochemical interactions, with engineering concepts motivated by specific biological problems.

Previous Edition TOC

 1. Introduction.

A. INTRODUCTION TO PHYSIOLOGICAL FLUID MECHANICS.

B. FUNDAMENTALS AND APPLICATIONS OF MASS TRANSPORT.

C. THE EFFECT OF MASS TRANSPORT UPON BIOCHEMICAL INTERACTIONS.

• A new chapter on Bioheat Transfer (Chapter 17) to address the growing need for information on this topic.

 

• Approximately 25% new problems, as well as 20% problems revised from the previous edition.

 

• Clarification of essential concepts based on feedback from students and instructors.

 

• Content and writing style streamlined throughout for enhanced readability.